Job Description

ACRC Trials is seeking a high-performing Clinical Operations Manager to lead and scale operations across multiple research sites. This is a critical leadership role for someone who thrives in a fast-paced environment, takes ownership, and drives both people performance and operational excellence.

In addition to overseeing existing sites, this role will play a key part in expanding our footprint across Texas, including leading the startup and launch of new research sites.

You will work directly with executive leadership to optimize workflows, elevate team performance, and ensure all studies are conducted at the highest level of quality, compliance, and efficiency.

Clinical Research Site Experience a MUST.

This is a full-time, on-site role based in Plano, TX. Travel within Texas is required (Current sites are in Plano, Frisco, Grapevine, Carrollton, and Austin.

Remote work is not available.

JOB DUTIES:

• Oversee day-to-day operations across multiple clinical research sites (Plano, Carrollton, Frisco, Grapevine)
• Travel regularly between sites to ensure consistency, performance, and quality standards are met
• Ensure studies are executed efficiently, on time, and in compliance with protocols, SOPs, and ICH-GCP guidelines
• Drive operational consistency, quality, and accountability across all locations
• Lead study start-up, enrollment performance, and audit readiness
• Lead the startup, activation, and operational rollout of new research sites across Texas
• Lead, mentor, and develop Clinical Research staff and site leadership
• Build a high-performance culture focused on ownership, accountability, and continuous improvement
• Conduct regular performance reviews, coaching, and professional development
• Partner with leadership on hiring, onboarding, and retention strategies
• Ensure all studies are audit-ready at all times (Sponsor, FDA, internal QA)
• Oversee training, regulatory compliance, and documentation standards
• Maintain strict adherence to patient safety, protocol requirements, and data integrity
• Identify and implement process improvements to increase efficiency and scalability
• Support development and refinement of SOPs and operational workflows
• Collaborate cross-functionally to align staffing, timelines, and study goals
• Champion adoption of new systems, tools, and technologies

We’re looking for someone who is:

• Highly accountable – takes ownership and delivers results
• Detail-oriented – understands that quality and compliance are non-negotiable
• A strong leader – can motivate, coach, and elevate teams
• Operationally sharp – able to manage complexity and drive execution
• Proactive and solutions-driven – identifies problems and fixes them
• Flexible and willing to travel regularly across Texas to support site operations and expansion\

REQUIRED EXPERIENCE

• 5+ years of clinical research experience (site-level required)
• 1–2+ years in a leadership or management role
• Strong understanding of FDA regulations, ICH-GCP, and clinical trial operations
• Experience managing multiple studies and/or sites

PREFERRED

• Advanced degree (MD, RN, NP, PA, PhD or equivalent)
• CCRC or equivalent certification
• Vaccine or high-enrolling site experience

WHY JOIN ACRC TRIALS?

• Work with one of the top-performing research site networks in the country
• Direct exposure to executive leadership and strategic decision-making
• Opportunity to build, launch, and scale new research sites across Texas
• Fast-paced, high-impact environment where your work directly advances medicine

More about ACRC Trials

ACRC Trials is an investigator site network of award-winning physician practices and clinics, specializing in vaccine trials, Phase II-IV pharmaceutical and device studies.

Our location at West Plano Medical Village, a master planned facility that offers primary care and complements it with open-access to independent specialty practices and convenient services, allows us to offer a distinct level of service to the medical research community.

With an emphasis on excellence, reliability, and volunteer care, ACRC Trials is one of the leading research institutions in the US. ACRC Trials is committed to upholding the highest standards of quality in implementing clinical research studies and managing volunteer safety. We have an outstanding reputation of providing great data and meeting our commitments with efficiency and integrity. ACRC Trials has preferred partnerships with most Sponsors and CROs.

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